Progeria comes from the Greek and Latin and means “premature aging”. The disease was first described in 1886 by Jonathan Hutchinson and Hastings Gilford. The most striking feature is the premature aging of the affected children.
The disease also called Progeria infantilis, is a disease feature of various genetic disorders, which is associated with overaging in children, such as Cockayne syndrome, Acrogerie, Geroderma osteodysplastica, Bloom syndrome or Xeroderma pigmentosum.
The affected children are suffering et al at:
- stunted growth
- bone loss
- faster skin aging
- hair loss
- joint changes
In adults, there is also the form of Progeria adultorum – also called Werner syndrome. This leads to a significantly accelerated aging process in adults, from about mid-life.